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PDRN Skin Barrier Repair Cream.

PDRN Skin Barrier Repair Cream.

 4.7 12k Happy Customers.

check_circle Strengthens the Skin Barrier.

check_circle Delivers Long Lasting Hydration.

check_circle Calms Stressed, Irritated Skin.

Regular price $35.99
Regular price $35.99 Sale price $70.99
SAVE 49% Sold out

LIMITED STOCK.

PDRN Skin Barrier Repair Cream.

PDRN Skin Barrier Repair Cream.

Regular price $35.99
Regular price $35.99 Sale price $70.99
SAVE 49% Sold out
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What Is PDRN?

PDRN (Polydeoxyribonucleotide) is a skin-supporting ingredient derived from salmon DNA that is widely used in advanced K-beauty and dermatologist-inspired skincare. It helps support the skin’s natural recovery process, strengthen the skin barrier, and improve moisture retention making skin less prone to dryness, irritation, and sensitivity. When used consistently, PDRN helps skin look calmer, smoother, and more balanced by reinforcing the barrier that protects and hydrates the skin, especially when paired with deeply hydrating ingredients like hyaluronic acid.

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How It Works.

This cream works by supporting the skin’s natural barrier and moisture system. PDRN helps the skin recover from stress and reinforces the barrier, while multiple forms of hyaluronic acid deliver deep hydration and help lock in moisture. Together, they strengthen the skin’s ability to retain water, reduce dryness and irritation, and leave skin feeling calm, smooth, and comfortably hydrated throughout the day without a heavy or greasy finish.

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Shipping Time.

Processing Time.
All orders are processed within 1–2 business days. You will receive a confirmation email as soon as your order is shipped.

Shipping Time
Estimated delivery times:

  • United States: 5–10 business days.
  • Worldwide: 6-12 business days.
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+87,500 Skin Saved.

  • Life Saving.

    My skin was constantly tight and irritated, especially after washing my face. No matter how many moisturizers I tried, the dryness always came back within an hour. After using this cream consistently, my skin feels calm, comfortable, and properly hydrated again. It absorbs quickly, doesn’t feel heavy, and my skin finally feels balanced.

    Jennifer

  • Boosted Confidence.

    I have issues with all moisturizers, my face becomes extremely greasy, so I’ve gone years not using any kind moisturizers for my face. This PDRN became my faces dream!! It is an amazing product, it absorbs fast and your skin will love it. I’ve had so many compliments and friends buy and they were all impressed.

    Jordan

  • Stress Gone.

    I overused exfoliants and retinol and completely wrecked my skin barrier. My skin felt sensitive and uncomfortable all the time. This cream helped restore hydration and made my skin feel stronger and smoother over time. It’s lightweight, soothing, and keeps my skin feeling comfortable throughout the day.

    Amber

    30 Day No Results Money Back Guarantee.

    We’re confident you’ll feel the difference in your skin but if your skin doesn’t feel calmer, more comfortable, and better hydrated after using PDRN Skin Barrier Repair Cream as directed, you’re covered. Try it risk-free for 30 days, and if you’re not satisfied for any reason, we’ll give you a full refund. No stress. No hassle.

    • CLEAN INGREDIENT.

    • THIRD PARTY TESTED.

    • NO SIDE EFFECT.

      How To Use.

      After cleansing, dispense a small amount using the applicator tip. Gently apply an even layer across your face and pat until fully absorbed. Use morning and night as the final step in your skincare routine to help restore hydration, calm the skin, and support a stronger skin barrier.

      What Is Skin Barrier?

      The skin barrier is the outermost layer of your skin that helps lock in moisture and protect against external stressors like pollution, weather, and harsh skincare. When this barrier is weakened, skin can feel dry, irritated, or sensitive because hydration escapes more easily. PDRN Skin Barrier Repair Cream is designed to help support and strengthen the skin barrier by delivering deep hydration and skin-revitalizing ingredients that help the skin retain moisture, feel calmer, and maintain a healthier, more balanced appearance with daily use.

      Dermatologist Approved.

      Our formula was carefully developed with skin barrier health as a top priority and reviewed by a licensed dermatologist. Each ingredient was evaluated for safety, skin tolerance, and suitability for daily use, including on sensitive or easily irritated skin. This review process helps ensure the formula meets high dermatological standards for comfort and effectiveness, without relying on harsh or unnecessary additives. The result is a lightweight, barrier supporting cream you can confidently use every day to help maintain hydration, comfort, and long term skin balance.

      Got A Question? We've Got You.

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      What skin types is this product suitable for?

      PDRN Skin Barrier Repair Cream is suitable for all skin types, including dry, sensitive, and irritation prone skin. It’s designed to support the skin barrier without feeling heavy or greasy.

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      What does PDRN do for my skin?

      PDRN is a skin supporting ingredient that helps promote moisture retention and supports the skin’s natural recovery process, making skin feel calmer, smoother, and more balanced over time.

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      Can I use this if my skin is sensitive?

      Yes. The formula was developed with skin tolerance in mind and reviewed by a licensed dermatologist. It’s free from harsh or unnecessary additives and suitable for daily use on sensitive skin.

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      How often should I use it?

      Use morning and night as the final step in your skincare routine. Consistent daily use helps maintain hydration and support a healthy skin barrier.

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      Can I use this with active ingredients like retinol or acids?

      Yes. This cream is ideal for pairing with active ingredients, as it helps support hydration and comfort when the skin feels dry or stressed.

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      How long does one bottle last?

      With regular daily use, one bottle typically lasts several weeks, depending on the amount applied per use.

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      What if it doesn’t work for me?

      We offer a 30-day no results money back guarantee. If you don't see your skin repairing, simply contact us for a full refund no hassle.

      • Matilda

        Am 44yr i have been dealing with unhealthy skin barrier for a long time and I wish I knew about this product earlier because my face feel so much better and shiner. I feel like am young.

      • Nikki

        I use this everyday, and will be reordering in the future. I love the little spout dispenser. It leaves skin feeling soft and hydrate., Love the light blue color, it's scentless and its a 80ml supply

      • Emilly

        I am in love with this product. My expectation was low when I got is but girl this is a game changer. I already have 3 on the way.

      • JP

        This face lotion/cream is pretty nice. You also get a lot for the price. It's very hydrating and feels soothing on the skin... especially in slightly irritated or dry areas. It doesn't really have a smell

      • Zahara

        I have never felt this confident. Used to have a lot of dryness and irritation, but they are gone. Highly recommend this product